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Alireza Khosravi

Alireza Khosravi , MD

Full Professor



School :

School of Medicine

Department :

Department of Cardiology

Research Center :

Hypertension Research Center

work address :

Hypertension Research Center, Cardiovascular Research Institute, Shahid Rahmani Alley, Moshtagh 3rd Street, Isfahan, Iran.

Education :

Professor of Cardiology Doctor of medicine (M.D), Isfahan University of medical sciences, Iran. (1985-1992) Cardiologist, Department of cardiology, Isfahan University of medical sciences. Isfahan, Iran. (1995-1999) Fellowship of Interventional Cardiology. Isfahan University of medical sciences. Isfahan, Iran. (2007-2009) Different professional educational courses in different techniques in peripheral and coronary intervention from Italy, Belgium, Germany, Frances.

Relevant Work Experience :

Date of Birth:            21.03.1967 Nationality:                Iranian Office Address: Hypertension Research Center, Cardiovascular Research Institute, Shahid Rahmani Alley, Moshtagh 3rd Street, Isfahan, Iran.          P.O Box:                  81465-1148, Isfahan, Iran. Office Phone:        +98 31 36115217 -36115216 Office Fax:             +98 31 36115217 E-mail:                    alirezakhosravif@gmail.com Department: Isfahan University of Medical Sciences, School of Medicine, Department of Cardiology Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Science Education Professor of Cardiology Doctor of medicine (M.D), Isfahan University of medical sciences, Iran. (1985-1992) Cardiologist, Department of cardiology, Isfahan University of medical sciences. Isfahan, Iran. (1995-1999) Fellowship of Interventional Cardiology. Isfahan University of medical sciences. Isfahan, Iran. (2007-2009) Different professional educational courses in different techniques in peripheral and coronary intervention from Italy, Belgium, Germany, Frances. Specific Duties and Responsibilities: Head of Hypertension Research center, Cardiovascular Research Institute, WHO Collaborating Center, Isfahan University of Medical Sciences, Isfahan, Iran Deputy of Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences Research and Educational Assistant of Isfahan Cardiovascular research institute Head of Interventional Cardiology field, Department of Cardiology, Medical school, Isfahan university of medical sciences Deputy Head of Angiography ward of the Isfahan Shahid Chamran hospital Head of Cardiovascular Diseases Working Group  Work Experience (Training Course): Coronary Intervention (13 years) peripheral vascular intervention (9 years) Participating in the German Heart Center, worked with Cardiac Team and participated in 10 structural heart cases. August 30-31, 2018, Munich. Germany. Participating in the Edwards SAPIEN 3 THV Fundamentals Training. September 4-5, 2018, Edwards EMEAC Headquarters-Nyon, Switzerland. Participating in the TTM Skill Training held at Charite Hospital, Berlin, Germany on November 22-23, 2016. Participating in the fellow in vascular intervention Leuven belgium2005 and 2009 Participating in the workshop of developed clinical trial in medical research 2003 Participating in the training workshop on the method of international classification of diseases ICD 10-1999. Participating in the workshop on Methods of Writing and Presenting Medical Articles, 1999. Supervised Thesis:   57 Published articles in journals: 154 Research Studies:  59

Professional Memberships & Qualification :

Extra Curricular Activities/ Interest(personal url) :



Grants & Awards :

Patents :

Presentations & Poster Sessions :

Determining the incidence of non-communicable and communicable diseases, recurrence rate, disease consequences, and mortality in a five-year prospective longitudinal cohort study based on a hospital registry of COVID 19 patients in Isfahan (Defeat COVID 19) Cohort Study. Screening of Hypertension in Adolescents to Achieve a map to the Implementation of a Cohort Study on Adolescents with Hypertension Background in Isfahan Province.  Development of national clinical practice guidelines for the Management, Diagnosis and Treatment of Acute Coronary Syndromes. Assessing the Impact of Training general practitonars the latest hypertension international and national Guidelines on Controlling their Under-Treatment Hypertensive Patients. Determining the prevalence of premature coronary heart disease and it’s risk factors according to different ethnicities and religions in Iran and developing a biobank for epigenetic studies Chronic Ischemic Cardiovascular Disease (CICD) Long-Term Registry. Percutaneous Coronary Intervention’s (PCI) Registry in Esfahan Iranian Registry of Percutaneous Coronary Interventions (Pilot). Updating Preparation Iranian Recommendations on Prevention, Evaluation and Management of High Blood Pressure (Guideline). Launching the first medical, research and educational center for high blood pressure in Isfahan. Validation of feed frequency questionnaire to assessment sodium intake and the share of food groups in receiving it in two age groups of adults, children and adolescents in Isfahan. Evaluation of the effect of self-care programs and localized treatment strategies on improving blood pressure control in Iran. Preparation of the First Iranian Recommendations on Prevention, Evaluation and Management of High Blood Pressure (Summary) Evaluation of urinary sodium in adult & children in Isfahan urban area. Designing a sensitization model for community and high-risk groups to reducing salt intake in Isfahan. Evaluation of sodium, chlorine and salt amounts in the main food sources of salt in Iranian society. Preparation of the First Iranian Recommendations on Prevention, Evaluation and Management of High Blood Pressure (Guideline). Improving the level of health in high risk and poor control employees (patients with high blood pressure) in Mobarakeh Steel Company (Complementary Plan) Assessment of salt intake per day based on the amount of urinary sodium chloride excretion in 24 hours in people older than 18 years of age in Isfahan and Najafabad. Assessment of the effect of treating cardiovascular risk factors on the risk of cardiovascular incidence in hypertensive patients in Isfahan's Folad-Mobarakeh workers. Assessment of cardiovascular incidence rate following administration of Osvix compared to Plavix after coronary artery stenting. Evaluation of national plan of the integrating for control HTN in the rural area of Isfahan. Comparative study of the effect of potassium salt and common salt on the blood pressure status of patients with hypertension The comparison of effect of low dose immediate release nicotinic acid with simvastatin on high level HDL-serum. The Effect of Health courier on Improving the Awareness and Performance of Nursing Staff in Educational and Social Security Hospitals to Prevent and Control Non-Communicable Diseases Healthy lifestyle for high-risk people in studying Isfahan healthy heart. Evaluation the relation between insulin resistance and restenosis after PTCA in non-diabetic ischemic patients Assessing the effect of educational interventions on the level of awareness of health care personnel regarding the control and treatment of cardiovascular and stroke diseases working in Isfahan, Najafabad and Arak health centers. Effect of metabolic syndrome score on atherosclerotic risk profile and coronary artery disease severity via angiography Evaluation of the trend of changes cardiovascular risk factors in people over 35 years old in three central cities of Iran. Evaluation of the level of awareness, performance and belief of general practitioners about the treatment of patients. Evaluation of the effect of nutritional interventions on increasing the awareness, attitude and nutritional performance of people in the community (healthy food project for a healthy society).

Research Experience :

Kelishadi, R Sharifi, Khosravi A et al. Relationship between C-reactive protein and atherosclerotic risk factors and oxidative stress markers among young person’s 10-18 years old Source: CLINICAL CHEMISTRY 2007;53(3):456-464 Arsang-Jang S, Mansourian M, Mohammadifard N, Khosravi A, Oveis-Gharan S, Nouri F, Sarrafzadegan N. Temporal trend analysis of stroke and salt intake: a 15-year population-based study. Nutr Neurosci. 2019 Sep 13:1-11. doi: 10.1080/1028415X.2019.1638665. [Epub ahead of print] Kelishadi R, Sadri G, Tavasoli A, Kahbazi M, Roohafza H, Sadeghi M,  Khosravi A, Sabet B, Amani A, Ansari R, Alikhasi H. Cumulative prevalence of risk factors for atherosclerotic cardiovascular diseases in Iranian adolescents: IHHP-HHPC. J Pediatr (Rio J). 2005 Nov-Dec; 81(6):447-53. Sarrafzadegan, N, Rabiei, K, Kabir A, Khosravi A, et al. Changes In Lipid Profile Of Patients Referred To A Cardiac Rehabilitation Program Source: European Journal Of Cardiovascular Prevention & Rehabilitation 2008; 15(4):467-472. Mohammadifard N, Marateb H, Mansourian M, Khosravi A, Abdollahi Z, Campbell R, Webster J, Petersen K, Sarrafzadegan N. Can methods based on spot urine samples be used to estimate average population 24 h sodium excretion? Results from the Isfahan Salt Study. Public Health Nutrition. 2020 Feb;23(2):202-213. Sarrafzadegan N, Kelishadi R, Dana Siadat Z, Esmaillzadeh A, Solhpour A, Shirani S, Naderi G, Asgary S, Sadri G, Khosravi A, Bahonar A. Obesity and cardiometabolic risk factors in a representative population of Iranian adolescents and adults in comparison to a Western population: The Isfahan Healthy Heart Programme. Public Health Nutr. 2010, 13(3), 314–323. Khosravi A, Mansouri A,  Shahsanayi F, Paydari N, Heshmat-Ghahdarijani K, Mansourian M, Nouri F, Taheri M, Farshidi H, Kazemi T, Khaledifar A, Assareh A, Behnammoghadam M, Peighambari M, Nematipour E, Sarrafzadegan N, Noohi F. Rationale and Design of the Persian Cardiovascular Disease Registry (PCVDR): Scale-Up of Persian Registry of Cardiovascular Disease (PROVE). Current Problems in Cardiology. Available online 12 March 2020, In Press, Corrected Proof. Gharipour M, Kelishadi R, Khosravi A, Shirani Sh, Masjedi M, Sarrafzadegan N. The impact of a community trial on the pharmacological treatment in the individuals with the metabolic syndrome: findings from the Isfahan Healthy Heart Program, 2001-2007. Arch Med Sci, 2012; 8(6):1009-1017 Khosravi A, Kelishadi R, Pourmoghaddas M, Shirani S, Asgari S,Khosravi M. Preprocedural C-reactive protein predictive value in angiographic in-stent restenosis after coronary stent placement in patients with stable angina . ARCHIVES OF MEDICAL SCIENCE 2009;5(2):166-171.   Oveisgharan S, Sarrafzadegan N, Shirani S, Khosravi A, et al. Stroke in Isfahan, Iran: hospital admission and 28-day case fatality rate: CEREBROVASCULAR DISEASES 2007: 24(6):495-499. Kelishadi R, Mokhtari M, Tavasoli A, Khosravi A, Ahangar-Nazari I, Sabet B, Kazemi A, Amini A. Determinants of tobacco use among youths in Isfahan, Iran. Int J Public Health. 2007; 52(3):173-9. Khosravi A, Gharipour M, Nezafati P, Khosravi Z, Sadeghi M7, Khaledifar A, Taheri M, Golshahi J, Sarrafzadegan N. Pre-hypertension, pre-diabetes or both: which is best at predicting cardiovascular events in the long term? Journal of Human Hypertension, 2017; 31(6):382-387. Khosravi A,Kiani mehr G,Kelishadi R,Shirani S,Gharipour M,Tavassoli A,Nouri F, Sarrafzadegan N.The impact of a 6-year comprehensive community trial on the awareness,treatment and control rates of hypertension in Iran:Experiences from the Isfahan healthy heart program. BMC cardiovascular disorders.2010;1-8. Sadeghipour P, Talasaz A, Eslami V, Gerayeli B, Vojdanparast M, Sedaghat M, Fakhr Moosavi A, Alipour Parsa S, Aminian B, Firouzi A, Ghafari S, Ghasemi M, Kazemi Saleh D, Khosravi A, Kojuri J, Noohi F, Pourhosseini H, Salarifard M, Salehi M, Sezavar H, Shabestari M, Soleimani A, Tabarsi P, Zand Parsa A, Abdi s. Management of ST-segment-elevation myocardial infarction during the coronavirus disease 2019 (COVID-1 9) outbreak: Iranian “247” National Committee's position paper on primary percutaneous coronary intervention. Catheterization and cardiovascular interventions.  2020 Apr 22. doi: 10.1002/ccd.28889. [Epub ahead of print] khosravi A, Mirdamadi A, Movahed MR. Successful Retrieval of Embolized Atrial Septal Defect Occluder and Patent Foramen Ovale Closure Device Using Novel Coronary Wire Trap Technique. Catheterization and Cardiovascular Interventions 2018; 92(1):189-192.            Tavassoli A, Gharipour M, Khosravi A, Kelishadi R, Dana Siadat Z, Bahonar A, Sadri G, Sadeghi M, Rabiei K, Sajadi F, Zarfeshani S, Eshrati B, Shirani S, Sarrafzadegan N. Gender Differences in Obesogenic Behavior, Socioeconomic and Metabolic Factors in a Population-based Sample of Iranians: The IHHP Study, J HEALTH POPUL NUTR 2010 Dec;28(6):602-609. Sarrafzadegan N, Gharipour M, Sadeghi M, Nezafati P, Talaie M,Oveisgharan S,Nouri F, khosravi A.Metabolic Syndrome and the risk of Ischemic Stroke.J Stroke Cerebrovasc Dis, Feb 2017;26(2):286-294. Mohammadi-Dolatabadi A, Vakhshoori M, Eghbali-Babadi M, Heidarpour M, Shafie D, Garakyaraghi M, Khosravi A. Comparison of multiple blood pressure frequency methods with optimum blood pressure measurement among Iranian individuals. Journal of Research in Medical Sciences.2020;1(40):1-6. Gharipour M,Ramezani M,Sadeghi M,Khosravi A,Masjedi M,Khosravi-Boroujeni H, Rafieian‑kopaei M,Sarrafzadegan N.Sex based levels of C‑reactive protein and white blood cell count in subjects with metabolic syndrome: Isfahan Healthy Heart Program. Journal of Research in Medical Sciences,2013;18:467-72. Khosravi A, Kelishadi R, Sarrafzadegan N, Boshtam M, Nouri F, Zarfeshani S, Esmailzadeh A. Impact of a community-based lifestyle intervention program on blood pressure and salt intake of normotensive adult population in a developing country. J Res Med Sci 2012; 17(3):235-241.  Shemirani H, Hemmati R, Khosravi A, Gharipour M, M Jozan. Echocardiographic assessment of inappropriate left ventricular mass and left ventricular hypertrophy in patients with diastolic dysfunction. J Res Med Sci, 2012; 17(2); 133-137. Tavassoli A, Gharipour M, Toghianifar N, Sarrafzadegan N, khosravi A, Zolfaghari B, Zarfeshani S. The impact of obesity on hypertension and diabetes control following healthy Lifestyle Intervention Program in a developing country setting. JRMS 2011; 16(Special Issue): 368-376. Sarrafzadegan N,Gharipour M,Ramezani M,Rabiei K,Zolfaghari B,Tavassoli A,Boshtam M,Zarfeshani S, Khosravi A,yousefi A. Metabolic syndrome and health-related quality of life in Iranian population.journal of research in medical sciences.2011;16(3):254-261. Khosravi A, Pourmoghaddas M, Ostovan M, Kiani Mehr G, Gharipour M, Zakeri H, Soleimani B, Namdari M, Hassanzadeh M, Tavassoli A, Ghaffari S, Khaledifar A, Roghani F, Khosravi M, Sarami S, Kojouri J, Nouri F, Khosravi E, Jozan M, Sarrafzadegan N. The impact of generic form of Clopidogrel on cardiovascular events in patients with coronary artery stent: results of the OPCES study. JRMS 2011; 16(5): 640-650. Mohammadifard N, Khaledifar A,  khosravi A, Nouri F, Pourmoghadas A, Feizi A, Esmailzadeh A, Sarrafzadegan N. Dietary sodium and potassium intake and their association with blood pressure in a non-hypertensive Iranian adult population: Isfahan salt study. Nutrition & Dietetics. 2017; 74(3):275-282.  Kelishadi R,Derakhshan R,Sabet B,Sarrafzadegan N,Kahbazi M, Sadri G.H ,Tavasoli A.A,hHeidari A,khosravi A, Amani A, Tolouei HR, Bahonar A,Rezaei Ashtiani AA,Moatarian A. The metabolic syndrome in hypertensive and normotensive subjects:the Isfahan healthy heart program. Annals Academy of Medicine,2005,34(3):243-9. Kelishadi R, Sarrafzadegan N, Sadri G, Pashmi R, Mohammadifard N, Tavasoli A, Amani A, Rabiei K, Khosravi A, Bahonar A .Short-Term Results of a Community-Based Program on Promoting Healthy Lifestyle for Prevention and Control of Chronic Diseases in a Developing Country Setting: Isfahan Healthy Heart Program. Asia Pac J Public Health. 2011:23(4),518-533. Beigi A,Sadeghi A.M, Khosravi A,Karami M,Masoudpour H.Effects of the arteriovenous fistula on pulmonary artery pressure and cardiac output in patients with chronic renal failure.journal of vascular access.2009;10(3).160. Khosravi A, Ramezani M,Toghianifar N, Rabiei K, Jahandideh M, Yousofi A. Association between Hypertension and quality of life in a sample of Iranian adults. ACTA Cardiol, Aug2010:65(4);425-430. Sarrafzadegan N, Rabiei K, Kabir A, Sadeghi M, Khosravi A, Asgari S, Taghipour HR, Roohafza H. Gender differences in risk factors and outcomes after cardiac rehabilitation. Acta Cardiol. 2008 Dec; 63(6):763-70. Etemadifar S, Bahrami M,Shahriari M, Khosravi A. Family Caregivers’ Experiences of Caring for Patients With Heart Failure: A Descriptive, Exploratory Qualitative Study. Journal of Nursing Research, 2015:23(2):153-161.  Mohammadifard N, khosravi A, Esmailzadeh A,Feizi A, Abdollahi Z, Salehi F, Sarrafzadegan N. Rationale, design and Initial Findings: Validation of simplified tools for Assessment of sodium intake in Iranian population. Archives of Iranian Medicine. September 2016;19(9):652-658.  Haghighatdoost F,Sarrafzadegan N,Khosravi A,Noori F,Boshtam M,Mohammadifard N,Abdollhi Z,Azadbakht L.Is the association between salt intake and blood pressure mediated by body mass index and central adiposity?. Archives of Iranian medicine.2013;16(3):167.  Mohammadifard N, Fahimi S, Khosravi A, Pouraram H, Sajedinejad S, Pharoah P, Malekzadeh R, Sarrafzadegan N, Advocacy Strategies and Action Plans for Reducing Salt Intake in Iran. Archives of Iranian Medicine, 2012; 15(5): 320 – 324.  Mohammadifard N, Karimi G, Khosravi A, Sarrafzadegan N, Jozan M, Zahed P, Haghighatdoost F.High dietary acid load score is not associated with the risk of metabolic syndrome in Iranian adults. Int J Vitam Nutr Res. 2020 Feb 5:1-12. doi: 10.1024/0300-9831/a000626. [Epub ahead of print] Khosravi A, Mohammadifard N, Gharipour M, Abdollahi Z, Nouri F, Feizi A, Jozan M, Sarrafzadegan N. Low correlation between morning spot and 24-hour urine samples for estimating sodium intake in an Iranian population: Isfahan Salt Study. Int J Vitam Nutr Res. 2019 Mar 19:1-7. doi: 10.1024/0300-9831/a000558. [Epub ahead of print] Khosravi A, Raoufi A, Pourmoghadas M, Paydari N, Gharipour M, Namdari M, Khaledifar A, Khosravi M, Bahonar A, Ostovan M, Hasanzadeh M, Sarrafzadegan N. Late clinical events of drug eluting versus bare metal stenting; OPCES’ ancillary study. Pak J Med Sci, 2013; 29(1):258-263. Khosravi A Toghianifar N, Sarrafzadegan N, Gharipour M, Azadbakht L. Salt intake, obesity, and pre-hypertension among Iranian adults: A cross-sectional study. Pak J Med Sci, 2012; 28(2):297-302   Shirani S, Kelishadi R, Sarrafzadegan N, Khosravi A, Sadri G, Amani A, Heidari S, Ramezani M. Awareness, treatment and control of hypertension, dyslipedemia and diabetes mellitus in an Iranian population: the IHHP study. East Mediterr Health J, Nov-Dec2009, 15(6);1455-63. Shahrokhi S, Kelishadi R, Sarrafzadegan N, Khosravi A, Roohafza H, Pooya A, Mollabashi R. Evaluation of the Quit and Win contest for smoking cessation in the Islamic Republic of Iran. East Mediterr Health J. Dec 2008, 14(6):1270-9. Najafian J, Toghianifar N,Khosravi A.Exertional abdominal pain as a symptom of secondary pulmonary hypertension in mitral stenosis. Nigerian journal of clinical practice.2013;16(1):110. Eghbali M, Feizi A, Khosravi A, Sarrafzadegan N. The Effect of Training on Knowledge, Attitude, and Practice in Patients with Hypertension; the Application of the Expanded Chronic Care Model: A Clinical Trial Study. Iranian Red Crescent Medical Journal. May 2018;20(5): DOI: 10.5812/ircmj.61693   Khosravi A,Pourmoghaddas M,Kelishadi R,Sabet B,Ansari R,Shirani SH,Sarraf zadegan N. Trends in blood pressure level, prevalence of hypertension and its care in Isfahan. IRCMJ-Iranian Red Crescent Medical Journal , 2005,8(2):62-68. Gharipour M, Kelishadi R, Toghianifar N, Tavassoli A, Khosravi A, Sajadi F, Sarrafzadegan N. Socioeconomic Disparities and Smoking Habits in Metabolic Syndrome: Evidence from Isfahan Healthy Heart Program. Iran Red Crescent Med J.2011; 13(8):537-543. Rajabizadeh G, Ramezani M, Roohafza H, Pourdamghan N, Khosravi A, Rabiei K, Sarrafzadegan N, Toghianifar N, Zarfeshani S. Association between cigarette smoking and socio-demographics, lifestyle and mental health factors in a sampled Iranian population. Southeast Asian J TropMed Public Health 2011, 42(4):977-87.

Research Interests :

Chronic Ischemic Cardiovascular Disease (CICD) Long-Term Registry. Acute Coronary Events -A Multinational Survey of current managements Strategies



Teaching Experience :

Teaching Interests :