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mo_sharifi

Mohammadreza Sharifi , PhD

Associate Professor


  • Phone: +989131343410
  • Email: mo_sharifi@med.mui.ac.ir
  • Date of birth : 00
  • CV: Curriculum Vitae_1.pdf (180.96 KB)

School :

School of Medicine

Department :

Department of Genetics and Molecular Biology

Research Center :

Pediatric Inherited Diseases Research Center

work address :

Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81744-176, Iran.

Education :

Ph.D., Molecular Medicine              Isfahan University of Medical Sciences                4                  2013 MSc, Hematology                          Tarbiat Modares University, Tehran                       2                 1999 Course, Cytothechnology               Tehran University of Medical Sciences                 1                  1995 BS, Medical laboratory Sciences            Isfahan University of Medical Sciences         4                   1997

Relevant Work Experience :

Mohammadreza Sharifi Associate Professor of Molecular Medicine Department of Genetics and Molecular Biology, School of Medicine Pediatric Inherited Diseases Research Center Research Institute for Primordial Prevention of Non-communicable Disease Isfahan University of Medical Sciences

Professional Memberships & Qualification :

Iran's first graduating Ph.D. in Molecular Medicine                                                                      2013 Rank 1 in Ph.D. of Molecular Medicine, Isfahan University of Medical Sciences                     2013 Winner of Shahid Motahari Award for Top-ranked education                                                  2012 Winner of Shahid Rajai Award for National employee                                                                2001 The top student in the Department of Anatomy and Molecular Biology                                        2011 Top expert of the Ministry of Health and Medical Education                                                     2002

Extra Curricular Activities/ Interest(personal url) :



Grants & Awards :

Patents :

Presentations & Poster Sessions :

1- Inhibition of microRNA miR-182 with Locked Nucleic Acid (LNA) technology and evaluation of its inhibitory effects on proliferation and expression of CASP9 in human breast cancer cells 2- Evaluation of overexpression of miRNA hsa-let7c-5p on cell proliferation, apoptosis and necrosis in human acute erythroleukemia cells. 3-  Knockdown of long non-coding RNA PVT1 with Antisense locked nucleic acid (LNA) GapmeRs technology and evaluation of its inhibitory effects on proliferation and apoptosis of human Acute Erythritroleukemia (AEL) cells 4- Long non-coding RNA SENCR, microRNA-29a, ETS-1 Transcription Factor, Promoter, Methylation and Early-onset Coronary Artery Disease  5- Study of the association between polymorphisms related to miR-146a and miR-3622a binding site and genes involved in warfarin metabolism (CYP2A6, VKORC1, CALU, GGCX, GATA4) and plasma level of 7-hydroxywarfarin with warfarinmaintenance  dose requirements among patients referring to Tehran Heart Center from 2017 to 2018  

Research Experience :

1- Najafi Z, Sharifi M, Javadi G. Degradation of miR-21 induces apoptosis and inhibits cell proliferation in human hepatocellular carcinoma. Cancer gene therapy. 2015;22(11):530-5. 2- Sharifi M, Moridnia A. Apoptosis-inducing and antiproliferative effect by inhibition of miR-182-5p through the regulation of CASP9 expression in human breast cancer. Cancer gene therapy. 2017;24(2):75-82. 3- Ziaeea S, Boroumandb MA, Salehia R, Sadeghianc S, Hosseindokhta M, Sharifi M. Non-invasive diagnosis of early-onset coronary artery disease based on cell type-specific gene expression analyses Biomedicine & Pharmacotherapy. Biomedicine & Pharmacotherapy. 2018;108:1115-22. 4- Sharifi M, Moridnia A, Mortazavi D, Salehi M, Bagheri M, Sheikhi A. Kefir: a powerful probiotics with anticancer properties. Medical Oncology. 2017;34(11). 5- Mortazavi D, Sharifi M. Antiproliferative effect of upregulation of hsa-let-7c-5p in human acute erythroleukemia cells. Cytotechnology. 2018:1-10.

Research Interests :



Teaching Experience :

Teaching Interests :