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GhadamAli Khodarahmi , PhD

Full Professor



School :

School of Pharmacy and Pharmaceutical Sciences

Department :

Department of Medicinal Chemistry

Research Center :

Isfahan Pharmaceutical Sciences Research Center

work address :

Education :

Educational Background Post-Doctoral  Fellowship in Synthesis and Cytotoxic Evaluation: Anti cancer Drugs 2002 - 2003 National Taiwan University,Taipe Taiwan PhD in Medicinal Chemistry: Drug design, Synthesis , Analysis 1993 - 1996 Welsh School of Pharmacy, Cardiff University, Cardiff, U. K pharm D 1983 - 1988 Fculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, IRAN

Relevant Work Experience :

Anticancer Drug Design and Synthesis

Professional Memberships & Qualification :

Extra Curricular Activities/ Interest(personal url) :



Grants & Awards :

Patents :

Presentations & Poster Sessions :

Research Experience :

Selected Publications 2017-2020  Monastrol derivatives: in silico and in vitro cytotoxicity assessments Journal: Research in Pharmaceutical Sciences, June 2020; 15(3): 249-262 Authers: Z Bidram, H Sirous, G. A Khodarahmi, F Hassanzadeh, N Dana, A.A Hariri, and M Rostami,*    Lactoperoxidase inhibition by tautomeric propylthiouracils Journal:Asian Journal of Green Chemistry, 2020, 4 (1), 1-10 Authors:M Soleimani, M Mirzaei*, MR Mofid, G Khodarahmi, SF Rahimpour   Synthesis and cytotoxic evaluation of novel quinozalinone derivatives with substituted benzimidazole in position 3 Journal: Research in Pharmaceutical Sciences, 2019; 14(3) 247-254 Authors: E Taherian, G.A. Khodarahmi*, M. Rahmani Khajouei, F Hassanzadeh and N Dana   Synthesis and cytotoxic evaluation of novel quinazolinone derivatives as potential anticancer agents Journal: Research in Pharmaceutical Sciences, October 2018; 13(5): 450-459 Authers: S Poorirani, S Sadeghian-Rizi, G A Khodarahmi, M Rahmani Khajouei, and Farshid Hassanzadeh*    Novel NGR anchored pullulan micelles for controlled and targeted delivery of doxorubicin to HeLa cancerous cells Journal: Iranian Polymer Journal 2018, 27 (4), 263-274 Authors: F Hassanzadeh, E Mahmoudi, J Varshosaz, G A Khodarahmi, M Rostami, M Ghanadian and N Dana   Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor Journal: Chemistry and Biodiversity 2018 Authers: A Ameri, G A Khodarahmi*, H Forootanfar, F Hassanzadeh and G H Hakimelahi.   Folic acid Targeted Polymeric Micelles based on Tocopherol succinate- Pulluan as an Effective Carrier for Epirubicin: Preparation, Characterization and In-Vitro Cytotoxicity assessment Journal: Current drug delivery 2017 (E-pub Abstract Ahead of Print Authors: F Hassanzadeh, M Mehdifar, J Varshosaz, GA Khodarahmi, M Rostami   Synthesis and cytotoxic evaluation of some novel quinoxalinedione diarylamide sorafenib analogues Journal: Research in Pharmaceutical Sciences, April 2018; 13(2): 168-176 Authers: M Khandan, S Sadeghian Rizi, G A Khodarahmi, and F Hassanzadeh*    Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety. Journal: Research in Pharmaceutical Sciences,  Feb 2018, 13(1), 82-92 Authers: S Sadeghian-Rizi, G A  Khodarahmi, A Sakhteman, A Jahanian-Najafabadi,   M Rostami, M Mirzaei and F Hassanzadeh   DFT Studies of Graphene–Functionalized Derivatives of Capecitabine Journal: Zeitschrift fur Naturforschung a, Sep 2017 Authers: M Aramideh, M Mirzaei, G A Khodarahmi and O  Gülseren   Biological evaluation, docking and molecular dynamic simulation of some novel diaryl urea derivatives bearing quinoxalinone moiety. Journal: Research in Pharmaceutical Sciences, 2017, 12(6), 500-509 Authers: S Sadeghian-Rizi, G A  Khodarahmi, A Sakhteman, A Jahanian-Najafabadi,   M Mirzaei and F Hassanzadeh   Synthesis, characterization, cytotoxic screening, and density functional theory studies of new derivatives of quinazolin-4(3H)-one Schiff bases Journal: Research in Pharmaceutical Sciences, 2017, 12(6), 444-455. Authors: R Rezaee Nasab, F Hassanzadeh, G A Khodarahmi,  M Mirzae, M Rostami1 and A Jahanian-Najaf abadi   Docking study, synthesis and antimicrobial evaluation of some novel 4-anilinoquinazoline derivatives Journal: Research in Pharmaceutical Sciences, October 2017; 12(5): 425-433 Authers: R Rezaee Nasab, F Hassanzadeh*, G A Khodarahmi, M Rostami, M Mirzaei, A Jahanian-Najafabadi and M Mansourian   Synthesis, characterization, molecular docking studies and biological evaluation of some novel hybrids based on quinazolinone, benzofuran and imidazolium moieties as potential cytotoxic and antimicrobial agents Journal: Iranian Journal of Basic Medical Sciences, Vol. 20, No. 9, Sep 2017 975-989 Authers: P Asadi, G.A Khodarahmi* A Jahanian-Najafabadi, L Saghaie and F Hassanzadeh    Biologically Active Heterocyclic Hybrids Based on Quinazolinone, Benzofuran and Imidazolium Moieties: Synthesis, Characterization, Cytotoxic and Antibacterial Evaluation Journal: Chemistry and Biodiversity 2017,Volume 14, Issue 4, 1-14 April 2017 e1600411 DOI: 10.1002/cbdv.201600411. Authers: P Asadi, G A  Khodarahmi*, A Jahanian-Najafabadi,  L Saghaei and F Hassanzadeh    Quantum mechanical / molecular mechanical and docking study of the novel analogues based on hybridization of common pharmacophores as potential anti-breast cancer agents Journal: Research in Pharmaceutical Sciences, 2017, 12(3), 233-240 Authers: P Asadi, G A  Khodarahmi*, H Farrokhpour, F Hassanzadeh and L Saghaei   Relaxations of methylpyridinone tautomers at the C60 surfaces: DFT studies Jurnal: International Journal of Nano Dimension 2017, 8 (2), 124-131 Authors: E Naderi, M Mirzaei, L Saghaie, G Khodarahmi, O Gulseren   Poly (ethylene-co-vinyl alcohol)-based polymeric thermo-responsive nanocarriers for controlled delivery of epirubicin to hepatocellular carcinoma Journal: Research in Pharmaceutical Sciences, April 2017; 12(2): 107-118. F Hassanzadeh, M Farzan, J Varshosaz, G A Khodarahmi, S Maaleki and M Rostami

Research Interests :

Research Project No: 397617 Title: Design, synthesis and cytotoxic evaluation of some novel benzimidazole and benzothiazole derivatives as potential Hsp70 inhibitors. This is one of our ongoing PhD projects supervised by me as the P.I and co-supervised by Dr Khosrow Kashfi, professor of pharmacology from City University of New York, School of Medicine and other colleagues from Isfahan faculty of pharmacy.  



Teaching Experience :

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