Grants & Awards :

1. Scholarship for PhD degree completion in the University of Alberta. Granted by Iranian Ministry of Health and Medical Education (2001)
2. Distinguished Researcher in Pharmaceutical Sciences, Isfahan University of Medical Sciences (2008)
3. Distinguished Researcher in Pharmaceutical Sciences, nominated by Isfahan Governorship (2010)
4. Distinguished Researcher in Bioinformatics, Isfahan University of Medical Sciences (2012)
5. Distinguished researcher for high h-index, nominated by the Ministry of Health and Medical Education (2016)
6. Distinguished researcher for high h-index, nominated by the Ministry of Health and Medical Education (2017)
7. Distinguished researcher for high h-index, nominated by the Ministry of Health and Medical Education (2018)
8. Distinguished researcher for high h-index, nominated by the Ministry of Health and Medical Education (2019)
9. Distinguished researcher for high h-index, nominated by the Ministry of Health and Medical Education (2020)
 

Patents :

Presentations & Poster Sessions :

Research Experience :

Research As a Supervisor of  Post-Doctoral Fellow, PhD, PharmD and MSc Thesis Projects:

Post-doctoral Fellow as Direct Supervisor:
Mahboubeh Rostami (PhD in Organic Chemistry from Chemistry department, Isfahan University), Design and Synthesis of 3-Hydroxy-Pyridine-4-One Derivatives as anti-HIV agents (2010-2011)

PhD Projects as Direct Supervisor:
1. Mohammad Hossein Askar Shamsi, PhD Thesis: Synthesis and biological evaluation of benzothiazole and benzyl piperidine derivatives based on 3-hydroxypridine-4-one (2017-2021)
2. Mehrdad Mohammad Pour, PhD Thesis: Synthesis and evaluation of acetylcholine esterase, amyloid Aβ aggregation inhibitory and antioxidant effects of new 3-Hydroxy pyridyn-4-one derivatives (2017-2021)
3. Pourya Shirvani, PhD Thesis: Design, synthesis and biological evaluation of some imidazole and indole-2-one derivatives as potential multi-target reverse transcriptase inhibitors and novel anti HIV-1 compounds (2015-2020).
4. Aylar Najafipour, PhD Thesis: Synthesis and evaluation of magnetic nanocomposites carrying methotrexate functionalized with LyP-1 peptide for targeted delivery of chemotherapeutics (2015-2020)
5. Tahereh Mostashari, PhD Thesis: Computer aided design and preparation of some imidazole and pyrroloimidazole compounds as anti-HIV-1 agents, with possible gp41 inhibitory activity (2015-2019)
6. Azizeh Asadzadeh, PhD Thesis: In vitro and in silico studies of the inhibitory effects of some novel Kojic acid derivatives on tyrosinase enzyme (2013-2015).
7. Saghi Sepehri, PhD Thesis: Design, synthesis and biological evaluation of some possible HIV-1 fusion inhibitors as novel anti-AIDS compounds (2012-2016)
8. Hajar Sirous-Najafabadi, PhD Thesis: Design, synthesis and biological evaluation of some potential integrase inhibitors as novel HIV-1 growth inhibitors (2012-2017).
9. Mohsen Shahlaei, PhD Thesis: Modeling of chemokine receptor CCR1 using Homology Modeling, Molecular Dynamic Simulation and Flexible Docking and application of various linear and nonlinear QSAR methods for predicting the activity of CCR1, CCR2 and CCR5 antagonists (2008-2012).
10. Razieh Sabet, PhD Thesis: Application of QSAR methods based on the MOLMAP approach for predicting and proposing synthesis of novel derivatives of 3- hydroxypyridine-4-ones with antibacterial and antifungal activity (2006-2011).
PhD Projects as Co-Supervisor:
11. Fahime Ghasemi, PhD Thesis: ProposingHIV-1 growth inhibitor compounds using nonlinear deep learning modeling and ligand-protein interaction (2015-2017)
12. Mohammad Nazifi, PhD Thesis: Synthesis and determination of Kpart values of some hydroxypyridinone derivatives coupled with polyamines and the evaluation of their cytotoxic effects (2016-2019)
13. Zohreh Bakherad, PhD Thesis:Design, synthesis and cytotoxic assay of novel 2,3-di(hetero)arylindole derivatives (2015-2019)
14. Neda Fyyazi, PhD Thesis: Molecular modeling and synthesis of some hybrid multi-target Iron chelators as potential antimalarial and anticancer agents by different in sillico methods (2017-2019)
15. Mahboubeh Mansourian, PhD Thesis: Study of the Human A2B adenosine receptor binding site by Homology Modeling, Molecular Dynamics simulations and Ligand Docking and study of quantitative Sutructure-Activity-Relationships using various QSAR methods (2009-2013).
MSc. Projects as Direct Supervisor:
16. Mansoureh Sattari, MSc Thesis: Preparation and evaluation of micro and nano properties of polyhydroxybutyrate particles and labling them with folic acid for targeted drug delivery to cancer cells (2010-2011)
17. Forough Rezaei, MSc Thesis: Synthesis and biological evaluation of novel leishmanicidal compounds having dual activity on iron absorption and interaction with DNA (2016-2018)
18. Vafa Sheikh Moradi, MSc Thesis: Synthesis and anti-leishmanial evaluation of some NO releasing antimony organometallic derivatives (2016-2017)
19. Ahmad Reza Salehi, MSc Thesis: Search for novel sodium-glucose co-transporter inhibitors using similarity search and structure-based virtual screening (2016-2018)
20. Shokooh Goodarzi, MSc Thesis: Investigation of linezolid analogues with the same antimicrobial activity using computational drug design method:structure- based virtual screening with molecular docking and dynamics (2020-2022)
21. Hossein Izadi Yazdkhasti, MSc Thesis: Virtual screening based on the molecular structure of proteins involved in cell survival and modulating compounds to find effective agents in the treatment of retinitis pigmentosa (RP) (2021-)

PharmD Projects as Direct Supervisor:
22. Vida Sheibini. Correction of structural defects in PDB files of druggable proteins in pathogenic parasites (2021-).

23. Javad Taherian. Correction of structural defects in PDB files of druggable proteins in pathogenic viruses and bacteria (2021-).
24. Moammadreza Amani. Correction of structural defects in PDB files of druggable proteins in pathogenic fungi (2021-).
25. Shiva sadat Hoseini, Study of the structural features of some benzimidazoles with acetylcholine esterase inhibitory activity using 3D-QSAR method and proposing possible inhibitors using molecular docking-based virtual screening (2020-).
26. Samane Hatami, Correction of structural defects in PDB files of soluble proteins in cancer signaling pathway (2020-2021).
27. Faride Haj akbari. Synthesis of some indane-2-one-hydrazone derivatives as potential anti-HIV agent and evaluation of their possible cytotoxicity (2020-).
28. NiushaAghaee.Design, synthesis and cytotoxic effects of some hydrazone derivatives of indole-2-one as potential inhibitors of tyrosine kinases (2019-).
29. Mahsa Zekri. Tyrosine kinase inhibitors, Virtual screening, molecular docking, 3D-QSAR (2019-).
30. Shahryar Moteshabes. Structural search for propossing some new FoxM1 protein inhibitors using virtual screening, molecular docking and 3D-QSAR (2019-).
31. Zeynab Zarrabi, Synthesis, molecular docking and antimetastatic assay of 4-aryl-1,2,3,4-tetrahydropyrimidine-5-carboxamide-2- one as potential Fascin inhibitor (2016-2018)
32. Nahid Tamiz, Molecular docking, synthesis and evaluation of novel compoundsas possible anti-HIV-1 agents (2016-2020)
33. Samira Gheisari, PharmD Thesis:Structure-based virtual screening of some 3-hydroxypyridine-4-one and 2,4-pyrimidine dione derivatives as possible inhibitors of hepatitis C virus polymerase by molecular docking method (2014-2018)
34. Parisa Rouhani, PharmD Thesis: Structure-based virtual screening of some 3-hydroxypyridine-4-one and 2,4-pyrimidine dione derivatives as possible inhibitors of endonuclease enzyme in influenza virus by molecular docking method (2014-2015)
35. Narges Riahi,PharmD Thesis: Synthesis, molecular docking and evaluation of cytotoxic effects of some Monastrol derivatives (2015-2018)
36. Alireza Zare, PharmD Thesis: Synthesis, experimental determination of partition coefficients of some novel derivatives of 3-hydroxypyridine-4-one using shake flask method and quantitative study of the relationship between the structure and partition coefficient (QSPR) of these compounds (2011-2013).
37. Sara Rafieepour Alavi, PharmDThesis: Conformational analysis of novel anti
HIV 1,2,3,4-Tetrahydropyrimidones (2011-2013)
38. Mohammad Mahmoudzadeh, PharmD Thesis: Synthesis of a novel chitosan derivative for the preparation of polymeric nanoparticles applicable in targeted drug delivery systems (2009-2012).
39. Maryam Mansouri, PharmD Thesis: Synthesis and antioxidant evaluation of ester derivatives of 4-furyl-3,4-dihydropyrimidine-2-thione-5-carboxylic acid (2009- 2012).
40. Kowsar Rezaie, PharmD Thesis: Synthesis and antimicrobial evaluation of novel Schiff base derivatives of 3-amino-2-methylquinazoline-4(3H)-one (2010-2011).
41. Maryam Roozkhosh, PharmD Thesis: Synthesis and antioxidant evaluation of novel amide derivatives of 3,4-dihydropyrimidine-2-one-5-carboxylic acid containing 1 -methyl-2-methylthio-imidazole-5-yl-substituent at C-4 position of 3,4-dihydropyrimidine ring (2009-2010).
42. Forough Talebian, PharmD Thesis: Synthesis and conformational analysis of novel potential antitubercular1,4-dihydropyridine-3,5-dicarboxamides (2009-2010).
43. Amir Sadeghi, PharmD Thesis: Synthesis of novel derivatives of 3-hydroxy-4-pyridinone containing Schiff base moiety at C-5 position of the ring in order to increase antioxidant activity of L1 (2009-2012).
44. Mehrdad Mohammadpour, PharmD Thesis: Synthesis of novel derivatives of 3-hydroxy-4-pyridinone containing hydrazone and oxime moiety at C-5 position of the ring in order to increase antioxidant activity of L1 (2009-2012).
45. Mehdi Azizpour, PharmD Thesis: Synthesis and Antimicrobial Evaluation of Novel Ester and Amide Derivatives of 4-(N1-benzyl-2-thiomethyl-5-imidazolyl)-1,2,3,4-tetrahydropyrimidine-2-one-Carboxylic Acid (2009-2010).
46. Ebrahim Khodadadi, PharmD Thesis: Synthesis and Antioxidant Evaluation of some novel 1, 4 dihydropyridine 3,5-dicarboxamide Compounds Possessing N1-methyl-2-benzylthio-imidazole-5-yl at the C4 Position of the Dihydropyridine Ring (2009-2011).
47. Bita Sedaghati, PharmD Thesis: Synthesis and Antimicrobial Evaluation of Novel Ester and Amide Derivatives of 1,2,3,4-tetrahyolropyrimidire-2-one-5-carboxylic acid Containing N1-anilino-2- methylthio-5- imidazolyl in the 4-Position of the Pyrimidine Ring (2008-2010).
48. Shirin Arbabi, PharmD Thesis: Synthesis and Evaluation of Antimicrobial
Activity of Novel Esters of 3,4-dihydropyrimidine-2-thione-5-carboxylates Containing-4-(N1-benzyl-2-methylthio-5-imidazolyl) Substitutent at C-4 Position of the Dihydropyrimidine Ring (2008-2010).
49. Behzad Dorkhosh, PharmD Thesis: Synthesis and Antimicrobial Evaluation of Cyclic Hydrazide-Hydrazones (2008-2010).
50. Soheila Rezaie, PharmD Thesis: Synthesis and Antimicrobial Evaluation of Novel Schiff Bases Prepared by the Reaction of 3-amino-2-phenylquinazoline-4(3H)-
one with 2-methylthio-imidazole-5-carbaldehyde Derivatives (2008-2010).
51. Alireza Sardari, PharmD Thesis: Synthesis and Antimicrobial Evaluation of Novel Derivatives of 1,2,3,4-tetrahydro pyrimidine thion (2008-2010).
52. Adel Omidi, PharmD Thesis: Synthesis and Evaluation of Antimicrobial Effects of Novel Derivatives of 4-(2-thienyl)–6–methyl-1,2,3,4-tetrahydropyrimidine-2-one-5-carboxamide (2008-2010).
53. Sajjad Zarepour, PharmD Thesis: Synthesis of Some Novel Pyrimidine Derivatives Using Biginelli Reaction (2007-2009).
54. Fateme Safari, PharmD Thesis: Synthesis and Quantitative Structure-Activity Relationship (QSAR) Analysis of 4-heteroaryl-2,6-dimethyl-3,5-bis N-phenyl(piperidyl)carbamoyl-1,4-dihydropyridineEffects (2008-2010).

55. Ghassem Bostaki, PharmD Thesis: Evaluation of Antimicrobial and Antifungal activity of Some Novel Iron Chelating Agents with the General Structure of Hydroxypyridinone and Hydroxypyranone (2007-2008).
56. Zahra Azadpour, PharmD Thesis: Synthesis of Some Novel Derivatives of 4-(2-methylthio-1-benzyl-5-imidazolyl)-2,6-dimethyl-3,5-bis-N-phenyl (pyridyl)carbamoyl-1,4-dihydropyridine as Potentially Active Antitubercular Agents (2006-2008).
57. Neda Delbari, PharmD Thesis: Synthesis of Some Novel Derivatives of 4-(2-methylthio-1-phenylamino-5-imidazolyl)-2,6-dimethyl-3,5-bis-N-phenyl(pyridyl) carbamoyl-1,4-dihydropyridine as Potentially Active Antitubercular Agents (2006-2008).
58. Majid Mansouri, PharmD Thesis: Synthesis of Some Novel derivatives of 4-(2-thienyl)-2,6-dimethyl-3,5-bis-N-phenyl (pyridyl) carbamoyl-1,4-dihydropyridine as Potentially Active Antitubercular Agents (2006-2008).
59. Mehrnaz Ghodratnama, PharmD Thesis: Synthesis of Some Novel Derivatives of 4-(1-methyl-1H-5-imidazolyl)-2,6-dimethyl-3,5-bis-N-phenyl (pyridyl)carbamoyl-1,4-dihydropyridine as Potentially Active Antitubercular Agents (2005-2007).
60. Ahmad Reza Narouni, PharmD Thesis: Synthesis and Pharmacological Evaluation of Novel Asymmetric Derivatives of 1,4-Dihydropyridine Compounds Containing N1-methyl-5-imidazolyl as C4 Substituent as Calcium Channel Blocking Agents (2004-2005).
61. Fateme Mohammadian, PharmD Thesis: Synthesis and Pharmacological Evaluation of Novel Symmetric Derivatives of 1,4-Dihydropyridine Compounds Containing N1-methyl-5-imidazolyl as C4 Substituent as Calcium Channel Blocking Agents (2004-2005).
PharmD Projects as co-supervisor:
62. Behzad Sartippour. PharmD Thesis: Synthesis and anti-tyrosinase evaluation of some novel derivatives of kojic acid (2011-2012)
63. Vahid Mirmohammadi, PharmD Thesis: Evaluation of cytotoxicity of some derivatives of 2-methyl -4(3H)-quinazolinones against tumor cell lines (Hela and MDA-MB-468) (2010-2012).
64. Azam Aghajani, PharmD Thesis: Cytotoxicity Evaluation of Some Derivatives 1,2,3, 4-Tetraydro-pyrimidin on HT-29 and Hela Cell Lines (2008-2010).
65. Mehdi Khorrami, PharmD Thesis: Cytotoxicity Evaluation of Some thienyl- and imidazolyl- 1,4-dihydropyridine-3,5 -dicarboxamides on HT-29 Cell Line (2007-2009).
66. Hoda Mojiri, PharmD Thesis: Pharmacological Evaluation of the Antiinflammatory and Analgesic Effects of Some Novel Derivatives of Hydroxy-4(1H)-Pyridinone (2007-2009).
67. Hamed Shabani, PharmD Thesis: Study on the Synthesis of Zinc Complexes of Bidentate Hydroxypyridinone and Hydroxypyranone Ligands and Determination of Some Physicochemical Properties of the Complexes (2007-2009).
68. Mohammad Reza Bakhshandeh, PharmD Thesis: Evaluation of the IC50 of 10 Novel 1,4 Dihydropyridine Calcium Channel Blocker Compounds with Acetyl Group in the C5 Position of the Dihydropyridine Ring instead of the Usual Ester Group (2005-2007).
69. Fereshteh Ahmadi, PharmD Thesis: Synthesis and Determination of Physicochemical Properties of Novel Hydroxypyranones as Iron (III) Bidentate Ligands (2004-2005).
70. Mohsen Sobhani, PharmD Thesis: Synthesis and Determination of Partition Coefficients of Some Hydroxypyranones as Iron (III) Chelators (2004-2006).
71. Maryam Amidi, PharmD Thesis: Evaluation of Contraction Inhibiting Effect of 10 Novel Dihydropyridine Calcium Channel Blocker Compounds on Ileum Smooth Muscle of Rat in Comparison with Nifedipine (2005-2006)

72. Mitra Mohajeri, PharmD Thesis: Synthesis of Derivatives of Phthalimides as Anxiolytic Agents (2004-2006).
73. Mohsen Shekofteh, PharmD Thesis: A Preliminary Study on Lovastatin Biosynthesis in Iran (2004-2005).
74. Omid Deilami, PharmD Thesis: Synthesis of Iron (III) Bidentate Ligands of 2-Ethyl-3-Hydroxy Pyridine-4-ones Effective in the Treatment of Malaria (2004-2005)

Research Interests :

Organic Synthesis

Computational Drug Design

Teaching Experience :

Teaching Interests :