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elham Jafari , PhDAssistant Professor
School :School of Pharmacy and Pharmaceutical SciencesDepartment :Department of Medicinal ChemistryResearch Center :work address :Department of Medicinal Chemistry and Isfahan Pharmaceutical SciencesResearch Center, School of Pharmacy and Pharmaceutical Science, Isfahan University of Medical Sciences, Isfahan, I.R.Iran. Education :Education: 1998 -2004: Pharm. D School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran Pharm.D dissertation titled as:" Preparation and evaluation of sustained release matrix tablets of terbutalin sulfate". Supervised by: Dr. Varshosaz .J and Dr. Emami J: (PhD, Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences) Sep 2005-2011: Ph.D course of Medicinal Chemistry Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran Ph.D thesis titled as: Synthesis and biological evaluation of novel 4-(3H)- quinazolinone derivatives Supervised by: Dr Hassanzadeh F and Dr Khodarahmi G.A (Ph.D, Department of Medicinal Chemistry, faculty of pharmacy, Isfahan University of medical science, Isfahan, Iran). Dr Hakimelahi G.H (Ph.D, Institute of chemistry, Academia Sinca, Nankang, Taipie, Taiwan) Dr Abedi D, (Ph.D, Department of microbiology, faculty of pharmacy, Isfahan University of medical science, Isfahan, Iran.Relevant Work Experience :1. Organic synthesis 2. Synthesis of heterocyclic compounds 3. Molecular modeling and computer aided drug designProfessional Memberships & Qualification :-Medical Council of Islamic Republic of Iran, Since 2004Extra Curricular Activities/ Interest(personal url) :Educational activities -Cell culture lab setup in biochemistry department (September 2010) Qualifications and Technical Skills: 1. Interpretation of 1HNMR and 13CNMR 2. Operation of FTIR apparatus 3. Interpretation of IR spectra 4. Interpretation of Mass spectra 5. Some techniques in organic synthesis 6. Synthesis, working up and purification of chemical compounds usingpreparative TLC, column chromatography and recrystalization 7. UV-Vis spectroscopy 8. Application of micro dilution for evaluation of antibacterial andantifungal activities of chemical compounds 9. Application of cell culture methods for evaluation of cytotoxicity ofchemical compounds 10. Application of some computational chemistry soft wares including ofHyperchem, Dragon, Gaussian, Matlab, Goromacs, Modeller and docking.Grants & Awards :Awards and Honors: Best pharmacy school students in Pharm.D course Top student in comprehensive test of basic sciences (2000). Top Student in PhD course Top student in the comprehensive board Exam of medicinal chemistry, July 2007, Member of center of talent student development (2001-2011). Selected Researcher in research week in Isfahan University of Medical Sciences (2011).Patents :nonePresentations & Poster Sessions :B: Abstracts in International Congress: 1. Elham Jafari, Farshid Hassanzadeh , Ghadamali Khodarahmi, "SYNTHESIS OF SOME FUSED QUINAZOLINONE DERIVATIVES" 4th international meeting on medicinal and pharmaceutical chemistry and 6th international symposium on pharmaceutical chemistry, September 30- October 2, 2010, Ankara, Turkey. C: Abstracts in Iranian Congress: 1. Shahtalebi. M, Daneshamoz. S, Jafari. E, Godarzi. S, Preparation of emulsion by Phase inversion temperature method (PIT) and role of concentration of surfactant mixtures. Poster presentation, 7th Iranian Pharmaceutical Students Seminar, March 2001, Isfahan, Iran. 2. Varshosaz.J, Emami.J, Jafari.E, Formulation of sustained release matrix tablets of Dimethyl fumarate for treatment psoriasis disease. Poster presentation, 9th Iranian Pharmaceutical Students. May 2003, Tabriz, Iran 3. Varshosaz.J, Emami.J, Jafari.E, Preparation and evaluation of sustained release matrix tablets of terbutalin sulfate, using hydrophilic natural gum. Poster presentation, 10th Iranian Pharmaceutical Students Seminar, October 2004, Mashhad, Iran 4.Varshosaz J, .Emami J, Jaffari.E, Comparison of hydrophilic natural gums and cellulosic polymers in formulation of sustained-release matrix tablets of terbutalin sulfate. Poster presentation. 10th Iranian Congress of Pharmaceutical Sciences, August 2006, Tehran, Iran 5. Hassanzade F, Jafari E. Supercritical Fluids. "Principle & Applications". Lecture Presentation. School of Pharmacy and Pharmaceutical Sciences, January 2007,Isfahan, Iran 6. Fassihi A, Jafari E, Combinatorial Chemistry." Principle & applications". Lecture Presentation. School of Pharmacy and Pharmaceutical Sciences, March 2008, Isfahan,Iran. 7. Elham jafari, Farshid Hassanzadeh, Ghadamali khodarahmi, Daryoush Abedi, Marzieh Rahmani. "Evaluation of Antibacterial Activity of Some New Cyclic Quinazolinone Derivatives" The 4th Iranian Congress of Clinical Microbiology, 9-11 Nov, 2010, Isfahan, Iran. 8.Marzieh Rahmani. Farshid Hassanzadeh,Ghadamali khodarahmi, Daryoush Abedi, Elham jafari, "Evaluation of Aantibacterial Effects of Some New Quinazolinone Derivatives" The 4th Iranian Congress of Clinical Microbiology, 9-11 Nov, 2010,Isfahan, Iran. 9. Marzieh Rahmani. Farshid Hassanzadeh, Ghadamali khodarahmi, Daryoush Abedi, Elham jafari, "Evaluation of Aantifungal Effects of Some New Quinazolinone Derivatives" The 4th Iranian Congress of Clinical Microbiology, 9-11 Nov, 2010,Isfahan, Iran. 10. Elham Jafari, Farshid Hassanzadeh, Ghadamali Khodarahmi, "Synthesis of new derivatives of quinazolinones" 12th Iranian pharmaceutical sciences congress (IPSC 2010), 2-5 August ,Zanjan, Iran. 11. E. Jafari, F. Hassanzadeh, G. Hakimelahi, G. Khodarahmi, M. Jalali. "Antibacterial, antifungal, and cytotoxic evaluation of some quinazolinone derivatives".13th Iranian pharmaceutical sciences congress (IPSC 2012), 3-6 September,Isfahan, Iran. 12. E. Jafari, G. Khodarahmi, F. Hassanzadeh, G. Hakimelahi, F. Tsai. "Synthesis of some new tricyclic 4(3H)-quinazolinone derivatives".13th Iranian pharmaceutical sciences congress (IPSC 2012), 3-6 september,Isfahan, Iran. 13. Synthesis and evaluation of antibacterial and antifungal activity of new cyclic imides derived from anhydride pthalic, succinic and maleic. 1th Iranian Medicinal Chemistry Seminar (IMCS). 17 &18 February, 2016, Kermanshah, Iran. 14. Prediction 3D structure of IGFBP3 using homology modeling and molecular dynamic. The 2nd Conference onProtein and Peptid Sciences, Univercity of Isfahan-27-28 April 2016. 15. Elham Jafari, Tahereh Mohammadi, Ali Jahanian-Najafabadi,, and Farshid Hassanzadeh Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives. 15th Iranian pharmaceutical sciences congress (IPSC 2017), october,Hamedan , Iran.Research Experience :1. Organic synthesis 2. Synthesis of heterocyclic compounds 3. Molecular modeling and computer aided drug designResearch Interests :1. Organic synthesis 2. Synthesis of heterocyclic compounds 3. Molecular modeling and computer aided drug designTeaching Experience :Teaching Assignments:Year/Semester Course title Role Fall 2005 Analytical chemistry Assistant Spring2006 Physico-chemical control Assistant Spring2006 Chemistry Assistant Fall 2006 Physico-chemical control Assistant Fall2007 Practice Pharmacy Lecturer Spring2008 Practice Pharmacy Lecturer Fall 2013 Organic chemistry Lecturer and assistant 2014 Homology modeling Lecturer 2015 General chemistry (practical) Assistant professor 2016 Organic chemistry Assistant professor 2016 General chemistry Assistant professor 2017 Organic chemistry and medicinal chemistry Assistant professor 2018 Medicinal chemistry &general chemistry Assistant professor 2019 Organic chemistry and medicinal chemistry Assistant professor 2020 Organic chemistry and medicinal chemistry Assistant professor 2021 Organic chemistry and medicinal chemistry Assistant professor Teaching Interests :Organic chemistry and medicinal chemistry , General chemistry, Analytical chemistry , Physico-chemical control |
