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	Mohammadreza Sharifi , PhD Associate Professor Google Scholar Research Gate Orcid Isid Scopus Phone: +989131343410 Email: mo_sharifi@med.mui.ac.ir Date of birth : 00 CV: Curriculum Vitae_1.pdf (180.96 KB) Personal information Research Teaching School : School of Medicine Department : Department of Genetics and Molecular Biology Research Center : Pediatric Inherited Diseases Research Center work address : Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81744-176, Iran. Education : Ph.D., Molecular Medicine Isfahan University of Medical Sciences 4 2013 MSc, Hematology Tarbiat Modares University, Tehran 2 1999 Course, Cytothechnology Tehran University of Medical Sciences 1 1995 BS, Medical laboratory Sciences Isfahan University of Medical Sciences 4 1997 Relevant Work Experience : Mohammadreza Sharifi Associate Professor of Molecular Medicine Department of Genetics and Molecular Biology, School of Medicine Pediatric Inherited Diseases Research Center Research Institute for Primordial Prevention of Non-communicable Disease Isfahan University of Medical Sciences Professional Memberships & Qualification : Iran's first graduating Ph.D. in Molecular Medicine 2013 Rank 1 in Ph.D. of Molecular Medicine, Isfahan University of Medical Sciences 2013 Winner of Shahid Motahari Award for Top-ranked education 2012 Winner of Shahid Rajai Award for National employee 2001 The top student in the Department of Anatomy and Molecular Biology 2011 Top expert of the Ministry of Health and Medical Education 2002 Extra Curricular Activities/ Interest(personal url) : Grants & Awards : Patents : Presentations & Poster Sessions : 1- Inhibition of microRNA miR-182 with Locked Nucleic Acid (LNA) technology and evaluation of its inhibitory effects on proliferation and expression of CASP9 in human breast cancer cells 2- Evaluation of overexpression of miRNA hsa-let7c-5p on cell proliferation, apoptosis and necrosis in human acute erythroleukemia cells. 3- Knockdown of long non-coding RNA PVT1 with Antisense locked nucleic acid (LNA) GapmeRs technology and evaluation of its inhibitory effects on proliferation and apoptosis of human Acute Erythritroleukemia (AEL) cells 4- Long non-coding RNA SENCR, microRNA-29a, ETS-1 Transcription Factor, Promoter, Methylation and Early-onset Coronary Artery Disease 5- Study of the association between polymorphisms related to miR-146a and miR-3622a binding site and genes involved in warfarin metabolism (CYP2A6, VKORC1, CALU, GGCX, GATA4) and plasma level of 7-hydroxywarfarin with warfarinmaintenance dose requirements among patients referring to Tehran Heart Center from 2017 to 2018 Research Experience : 1- Najafi Z, Sharifi M, Javadi G. Degradation of miR-21 induces apoptosis and inhibits cell proliferation in human hepatocellular carcinoma. Cancer gene therapy. 2015;22(11):530-5. 2- Sharifi M, Moridnia A. Apoptosis-inducing and antiproliferative effect by inhibition of miR-182-5p through the regulation of CASP9 expression in human breast cancer. Cancer gene therapy. 2017;24(2):75-82. 3- Ziaeea S, Boroumandb MA, Salehia R, Sadeghianc S, Hosseindokhta M, Sharifi M. Non-invasive diagnosis of early-onset coronary artery disease based on cell type-specific gene expression analyses Biomedicine & Pharmacotherapy. Biomedicine & Pharmacotherapy. 2018;108:1115-22. 4- Sharifi M, Moridnia A, Mortazavi D, Salehi M, Bagheri M, Sheikhi A. Kefir: a powerful probiotics with anticancer properties. Medical Oncology. 2017;34(11). 5- Mortazavi D, Sharifi M. Antiproliferative effect of upregulation of hsa-let-7c-5p in human acute erythroleukemia cells. Cytotechnology. 2018:1-10. Research Interests : Teaching Experience : Teaching Interests :

Provider

Mohammadreza Sharifi , PhD

Associate Professor

Phone: +989131343410
Email: mo_sharifi@med.mui.ac.ir
Date of birth : 00
CV: Curriculum Vitae_1.pdf (180.96 KB)

School :

School of Medicine

Department :

Department of Genetics and Molecular Biology

Research Center :

Pediatric Inherited Diseases Research Center

work address :

Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81744-176, Iran.

Education :

Ph.D., Molecular Medicine Isfahan University of Medical Sciences 4 2013 MSc, Hematology Tarbiat Modares University, Tehran 2 1999 Course, Cytothechnology Tehran University of Medical Sciences 1 1995 BS, Medical laboratory Sciences Isfahan University of Medical Sciences 4 1997

Relevant Work Experience :

Mohammadreza Sharifi Associate Professor of Molecular Medicine Department of Genetics and Molecular Biology, School of Medicine Pediatric Inherited Diseases Research Center Research Institute for Primordial Prevention of Non-communicable Disease Isfahan University of Medical Sciences

Professional Memberships & Qualification :

Iran's first graduating Ph.D. in Molecular Medicine 2013 Rank 1 in Ph.D. of Molecular Medicine, Isfahan University of Medical Sciences 2013 Winner of Shahid Motahari Award for Top-ranked education 2012 Winner of Shahid Rajai Award for National employee 2001 The top student in the Department of Anatomy and Molecular Biology 2011 Top expert of the Ministry of Health and Medical Education 2002

Extra Curricular Activities/ Interest(personal url) :

Grants & Awards :

Patents :

Presentations & Poster Sessions :

1- Inhibition of microRNA miR-182 with Locked Nucleic Acid (LNA) technology and evaluation of its inhibitory effects on proliferation and expression of CASP9 in human breast cancer cells 2- Evaluation of overexpression of miRNA hsa-let7c-5p on cell proliferation, apoptosis and necrosis in human acute erythroleukemia cells. 3- Knockdown of long non-coding RNA PVT1 with Antisense locked nucleic acid (LNA) GapmeRs technology and evaluation of its inhibitory effects on proliferation and apoptosis of human Acute Erythritroleukemia (AEL) cells 4- Long non-coding RNA SENCR, microRNA-29a, ETS-1 Transcription Factor, Promoter, Methylation and Early-onset Coronary Artery Disease 5- Study of the association between polymorphisms related to miR-146a and miR-3622a binding site and genes involved in warfarin metabolism (CYP2A6, VKORC1, CALU, GGCX, GATA4) and plasma level of 7-hydroxywarfarin with warfarinmaintenance dose requirements among patients referring to Tehran Heart Center from 2017 to 2018

Research Experience :

1- Najafi Z, Sharifi M, Javadi G. Degradation of miR-21 induces apoptosis and inhibits cell proliferation in human hepatocellular carcinoma. Cancer gene therapy. 2015;22(11):530-5. 2- Sharifi M, Moridnia A. Apoptosis-inducing and antiproliferative effect by inhibition of miR-182-5p through the regulation of CASP9 expression in human breast cancer. Cancer gene therapy. 2017;24(2):75-82. 3- Ziaeea S, Boroumandb MA, Salehia R, Sadeghianc S, Hosseindokhta M, Sharifi M. Non-invasive diagnosis of early-onset coronary artery disease based on cell type-specific gene expression analyses Biomedicine & Pharmacotherapy. Biomedicine & Pharmacotherapy. 2018;108:1115-22. 4- Sharifi M, Moridnia A, Mortazavi D, Salehi M, Bagheri M, Sheikhi A. Kefir: a powerful probiotics with anticancer properties. Medical Oncology. 2017;34(11). 5- Mortazavi D, Sharifi M. Antiproliferative effect of upregulation of hsa-let-7c-5p in human acute erythroleukemia cells. Cytotechnology. 2018:1-10.