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Mohammadali Sheikholeslam

Mohammadali Sheikholeslam , PhD

Assistant Professor



School :

School of Advanced Technologies in Medicine

Department :

Department of Biomaterials, Nanotechnology and Tissue Engineering

Research Center :

work address :

School of Advanced Technologies in Medicine,
Isfahan University of Medical Sciences
Hezar Jerib street, Isfahan, Iran 8174673461
Map: https://goo.gl/maps/WxjBDo4Myhy

Education :

PDF: University of Toronto, Sunnybrook Health Sciences Centre (2015-2019) Ph.D.: University of Waterloo (2009-2015) M.Sc.: Isfahan University of Technology (2005-2008) B.Sc.: Shahid Chamran University of Ahvaz (2000-2004)

Relevant Work Experience :

Mohammadali Sheikholeslam is an assistant professor at Isfahan University of Medical Sciences (IUMS). He obtained his B.Sc. and M.Sc. degrees in Materials Engineering from Shahid Chamran University of Ahvaz, (Iran, 2004) and Isfahan University of Technology (Iran, 2007) respectively. Later on, he moved to Canada in 2009 to pursue his academic studies and received his Ph.D. degree in Chemical Engineering (Nanotechnology) from University of Waterloo (Canada) in 2015. Then he moved to Toronto and spent four years as a PDF at the University of Toronto (Sunnybrook Health Sciences Centre & Department of Surgery) before going back to Iran in 2019. Ali’s research interests lie at the intersection of tissue engineering, disease modeling and nano-biomaterials. In particular he has studied applications of self-assembling peptides for dispersing carbon nanotubes, fabrication of mediator-less nano-biosensors, developing injectable peptide-CNT hydrogels, cancer cell spheroid formation (for tumor microenvironment studies) and tissue engineering. During his postdoc at UofT, he focused on skin regeneration specifically for burn patients and involved in different projects including skin tissue engineering (fabrication/modification of scaffolds using methods like electrospinning, lyophilization, soft lithography and 3D bioprinting of DECM), extracting AGWJ-derived exosomes from umbilical cord for wound healing and isolating burn-derived stem cells for skin regeneration. He is a big fan of AFM and tries to take advantage of this multifunctional tool in his research. In the big picture he is interested in scarless skin regeneration, cell and tumor microenvironment, disease modeling and immunoengineering and is going to employ different biomaterial/hydrogel and cell/organoid systems along with techniques like microfluidics and organ-on-a-chip devices to research on these topics. Besides the cutting-edge research, he also believes in product-oriented research that can be easily pushed toward commercialization down the road with a more tangible benefit to the clinic and society.

Professional Memberships & Qualification :

Summer-by-Design 2-weeks Workshop (University of Toronto) (2019) International Society for Stem Cell Research (ISSCR) 2017 Travel Grant from Medicine-by-Design (University of Toronto) (2017, Value $2000) UW Department of Chemical Engineering Scholarship Merit Award (W2015, Value: $1000) U of Waterloo International Doctoral Student Award (F2009-S2013, Value: $9660/year) U of Waterloo Graduate Research Studentship (F2009-W2015, Value: $21000/year) Iran Nanotechnology Initiative Council Scholarship (2008, Value: $2000)

Extra Curricular Activities/ Interest(personal url) :



Grants & Awards :

Patents :

Presentations & Poster Sessions :

Development of Shear-thinning Injectable Hydrogels for Biomedical Applications Investigation of the Role of Normal and Cancer-associated Fibroblasts and Integrin Α6β4 in Organotropism and Metastasis of Breast Cancer to Lung (Advisor) Reverse Engineering & Modification of LigaSure™ Laparascopic Sealer/Divider with Nano-coating Fabrication of a Simple and Economical Organ-on-a-chip Device

Research Experience :

1. Sheikholeslam, M.; Nanda, P.; Pritzker, M.; Chen, P. Immobilization, Direct Electrochemistry and Electrocatalysis of Hemoglobin on Peptide-Carbon Nanotube Modified Electrode, bioRxiv preprint doi: https://doi.org/10.1101/2020.06.16.153767 2. Sheikholeslam, M.; Wright, M.; Cheng, N.; Oh, H.; Wang, Y.; Datu, A. K.; Santerre, J. Paul; Amini-Nik, S.; Jeschke, M. Electrospun Polyurethane-Gelatin Composite: A New Tissue Engineered Scaffold for Application in the Skin Regeneration and Repair of Complex Wounds, ACS Biomaterials Science & Engineering, 2020, 6, 505-516. 3. Cheng, N.; Jeschke, M.; Sheikholeslam, M.; Datu, A.; Oh, H.; Amini-Nik, S. Promotion of Dermal Regeneration using Pullulan/Gelatin Porous Skin Substitute. Journal of Tissue Engineering and Regenerative Medicine, 2019, 13(11), 1965-1977. 4. Bakhtyar, N.; Jeschke, M.; Herer, E.; Sheikholeslam, M.; Amini-Nik, S. Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing. Stem Cell Research & Therapy, 2018, 9, 193. 5. Sheikholeslam, M.; Wheeler S.; Duke K.; Pritzker, M.; Chen, P. Peptide and Peptide-Carbon Nanotube Hydrogels as Scaffolds for Tissue & 3D Tumor Engineering. Acta Biomaterialia, 2018, 69, 107-119. 6. Sheikholeslam, M.; Wright, M. E. E., Amini-Nik, S., Jeschke, M. G. Biomaterials for Skin Substitutes. Advanced Healthcare Materials, 2018, 7(5), 1700897. 7. Sheikholeslam, M.; Pritzker, M.; Chen, P. Hybrid Peptide–Carbon Nanotube Dispersions and Hydrogels. Carbon, 2014, 71, 284–293. 8. Sheikholeslam, M.; Pritzker, M.; Chen, P. Dispersion of multi-walled carbon nanotubes in water using ionic-complementary peptides. Langmuir, 2012, 28, 12550–12556. 9. Sheikholeslam, M. A.; Raeissi, K.; Enayati, M. H. Study on Corrosion Behaviour of Nanocrystalline and Amorphous Co-P Electrodeposits, Transactions of the Institute of Metal Finishing, 2010, 88(6), 324-329. 10. Sheikholeslam, M. A.; Enayati, M. H.; Raeissi, K. Charracterization of Nanocrystalline and Amorphous Cobalt-Phosphorous Electrodeposits, Materials Letters, 2008, 62, 3629-3631. INVITED BOOK CHAPTER 1. Sheikholeslam, M; Pritzker, M. D.; Chen, P; “Electrochemical Biosensor for Glycated Hemoglobin (HbA1c)”, Book Chapter, Biosensors for Health, Environment and Biosecurity / Book 2, Intech-Open Access Publisher, Rijeka, Croatia, ISBN 978-953-307-443-6, 28 pages.

Research Interests :

Electrospun Gel-PU Scaffold Enzymatic Degradation Mechanism Injectable Shear-Thinning Composite Hydrogels for 3D Bioprinting and Drug Delivery Applications



Teaching Experience :

Teaching Interests :