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Roya Sherkat , MD


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  • Phone: 03137923929
  • Email: sherkat@med.mui.ac.ir
  • Date of birth : 00
  • CV: دکتر شرکت.pdf (634.88 KB)

School :

School of Medicine

Department :

Department of Infectious Diseases and Tropical Medicine

Research Center :

Acquired Immunodeficiency Research Center

work address :

Education :

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Relevant Work Experience :

International Collaboration with Other Researches and Academic Centers •Prof. Christophe Klein, Chair of Department of Pediatrics, Ludwig-Maximilians-University Munich and Adjunct Faculty of our Center •Dr. Jean-Laurent Casanova, head of Laboratory of Human Genetics of Infectious Diseases, imagine institute, Necker Hospital, Paris, France •Prof. Bodo Grimbacher, scientific director of Center for Chronic Immunodeficiency (CCI), University of Freiburg •Prof. Stephan Ehl, medical director of Center for Chronic Immunodeficiency (CCI), University of Freiburg •Prof. Johannes huebner Presence in our Center •Dr. Sebastian Hesse Presence in our Center •Dr. Daniel Petersheim Presence in our Center •Prof Manish Bute, University of California, Los Angeles (UCLA) •Prof. Joseph Curch, Children's Hospital Los Angeles (CHLA)

Professional Memberships & Qualification :

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia in" Nature Genetics" The phenotype of human STK4 deficiency in " Blood" Myb-like, SWIRM, and MPN domains 1 (MYSM1) deficiency: Genotoxic stress-associated bone marrow failure and developmental aberrations  in" J Allergy Clin Immunol. " Impaired IL-12- and IL-23-Mediated Immunity due to IL-12Rβ1 deficiency in Iranian Patients with Mendelian Susceptibility to Mycobacterial Disease  in" J Clin Immunol" EBV lymphoproliferative-associated disease and primary cardiac T-cell lymphoma in a STK4 deficient patient  in" Medicine"

Extra Curricular Activities/ Interest(personal url) :

Grants & Awards :

During collaboration with Prof. Christophe Klein (Chair of Department of Pediatrics, Ludwig-Maximilians-University Munich and Adjunct Faculty of our Center), we could obtain DAAD grant (The DAAD is the world's largest financial organization for the international exchange of students and researchers).

Patents :

Presentations & Poster Sessions :

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Research Experience :

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Research Interests :

ØGene mutations responsible for primary immunodeficiency disorders: A report from the first primary immunodeficiency biobank in Iran ØEBV lymphoproliferative-associated disease and primary cardiac T-cell lymphoma in a STK4 deficient patient.A case report ØInhibition of microRNA-21 via locked nucleic acid-anti-miR suppressed  tastatic features of colorectal cancer cells through modulation of programmed cell death 4 ØNocardial brain abscess in a patient with pulmonary alveolar proteinosis ØJAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia ØMyb-like, SWIRM, and MPN domains 1 (MYSM1) deficiency: Genotoxic stress-associated bone marrow failure and developmental aberrations ØAssociation Between Acute Infectious Mononucleosis and Vitamin D Deficiency ØClinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency ØPrimary Antibody Deficiency in a Tertiary Referral Hospital: A 30-Year Experiment ØInterleukin-10 receptor mutation presenting with severe nappy ulceration and infantile inflammatory bowel disease. Ø Proteome analysis of human neutrophil granulocytes from patients with monogenic disease using data-independent acquisition.

Teaching Experience :

Teaching Interests :