Grants & Awards :

1- spring 2020, appreciation from the vice president of medicine of Isfahan University of Medical Sciences

2- 2016, appreciation from the Deputy Health Minister of the Ministry of Health, Treatment and Medical Education for participating in the educational content of the national genetic counseling program.

3- 2012, 3rd place in the 6th educational festival of Shahid Motahari in the area of compiling and revising educational programs.

4- 2012, 6th research rank among 600 faculty members of Jundishapur University of Medical Sciences, Ahvaz.

5- Receiving letters of appreciation from the honorable head of the center of non-communicable diseases of the Ministry of Health for cooperation in the projects - in the years 2011 to 2020.

6- The best Ph.D student of Tehran University of Medical Sciences, Faculty of Medicine in the academic year 2009-2010.

7- The best researcher of the genetics department in PhD level in March 2018.

8- Discovery of a new genetic locus in autosomal recessive non-syndromic deafness named DFNB93 (approved by HUGO international nomenclature committee) in April 2010 and cooperation in finding the corresponding gene called CABP2 in 2012.

9- 2007, Received a grant from the European Genetics Foundation (ESGM) to participate in the medical genetics course, Bologna, Italy

Patents :

Presentations & Poster Sessions :

• Mendel’s 200th birthday, 2009 Belgium
• Annual conference of European Society of Human Genetics (ESHG) 2011
• The Sccond International congress of Cancer Genetics, Tehran
• The First International congress of Cancer Genetics, Tehran
• 3rd Iranian congress of genetic disorders and disabilities. Tehran
• 4rd Iranian congress of genetic disorders and disabilities. Tehran, 2004.
• 5rd Iranian congress of genetic disorders and disabilities. Tehran, 2004

Research Experience :

1- Investigating the genetic linkage of several loci involved in non-syndromic autosomal recessive deafness with deafness in 50 Iranian families with an Iranian deaf person.

2- Investigating the expression level of efflux pumps MexAB-OprM, MexXY-OprM, OprD purine, chromosomal beta-lactamase AmpC and mutations of regulatory genes mexR and mexZ and the existence of metallo-beta-lactamase genes in carbapenem-resistant Pseudomonas aeruginosa isolated from clinical samples in Imam Khomeini Hospital and Golestan Ahvaz city.

3- Investigating the existence of metallobetalactamase and oxacillinase coding genes in Acinetobacter baumannii isolated from clinical samples, bacterial typing through genomic fingerprinting using rep-PCR method and measuring the expression level of the efflux pump gene adeB through Real Time PCR.

4- Study of molecular genetics and genetic linkage of patients with Wolfram syndrome.

5- Genetic screening of deafness loci in samples of South Khorasan province.
6- Genetic linkage study of Iranian patients with non-syndromic deafness with autosomal recessive inheritance to common genetic loci.
7- Genetic Linkage and Genome-wide scan of Iranian patients suffering from non-syndromic autosomal recessive deafness
8- Investigating the relationship between CD4 gene polymorphism and vitiligo disease in Iranian population
9- Investigating the relationship between CD4 gene polymorphism and type 1 diabetes. Investigating the relationship between gene polymorphism

10- Investigating the relationship between APOE and ACE gene polymorphisms and coronary heart disease
11- Investigating the involvement of HRAS gene in thyroid cancers
12- Genetic Linkage and Genome-wide scan of Iranian patients suffering from non-syndromic autosomal recessive deafness in Isfahan province
13- link prediction in biological networks made from gene expression data related to breast cancer subtypes
14- Improving the estimation of the degree of damage of non-synonymous genetic variants with the help of cumulative models
15- Genetic mapping of short stature in inbreeding families in the mid-water area of Chahar Mahal Bakhtiari province
16- Implementation and optimization of the third stage of next generation sequencing (NGS) data analysis for hereditary deafness patients
17- In vitro study of the effect of carvacrol on hydatid cyst protoscolexes and the investigation of the increased expression genes of protoscolexes exposed to carvacrol using the RNA Seq method and its confirmation with the Real-time PCR method.

18- In vitro study of the effect of carvacrol on hydatid cyst protoscolexes and investigation of the decreased expression genes of protoscolexes exposed to carvacrol using the RNA Seq method and its confirmation with the Real-time PCR method
19- Investigating the effect of carvacrol on hydatid cyst protoscolexes in vitro and examining the altered genes expressed in the apoptosis pathway in protoscolexes exposed to carvacrol using the RNA Seq method and confirming it with the Real-time PCR method
20- Investigating the migration and differentiation of umbilical cord mesenchyme stem cells to the extracellular matrix treated with monophospholipid A and Lactobacillus casei juice
21- Genetic study of congenital adrenal hyperplasia (CAH) in Chaharmahal, Bakhtiari and Isfahan provinces.
22- Investigating acute and chronic toxoplasmosis in peritoneal dialysis, short-term, long-term hemodialysis patients and kidney transplant recipients using ELISA and PCR techniques in Central Province
23- Investigating the anticancer effects of curcumin and berberine nanomicelles and their combination with the standard drug 5-FU in breast cancer cells
24- Evaluation of the anti-tumor effects of LGK974 and Aspirin drugs in cell signaling pathways, cell cycle and apoptosis in colorectal cancer cell lines compared to the standard oxaloplatin drug.
25- Investigating genomic rearrangements and large mutations of MLH1 and MSH2 genes in patients of three large families with Lynch-like syndrome identified among patients with familial colorectal cancers living in Isfahan, Chaharmahal and Bakhtiari provinces.

26- Designing and implementing the optimal processing process for automatic analysis of new generation sequencing data related to hereditary deafness by open source tools.
27- Investigating three families with overt diabetes in young adulthood (MODY) to identify the genetic etiology profile using NGS method in the population of Isfahan province
28- Investigating the association of HNF1B, IPF1 genes in patients with suspected juvenile diabetes (MODY) in Isfahan city
29- Genomic investigation (exome sequencing) in a large family with severe to profound non-syndromic autosomal recessive deafness in order to identify the genetic cause
30- Evaluation and optimization of genotyping of short tandem repeat STR markers to trace the instability of microsatellites in order to make a kit
31- Genetic mapping of common autosomal recessive disease of short stature in an inbred Iranian population

Research Interests :

Medical Genetics

Gene mapping

Hereditary disease

Genetic of rare disease

 

Teaching Experience :

Medical ethics, genetic engineering, genetic updates, molecular epidemiology, molecular basis of diseases, molecular methods of disease diagnosis, immunogenetics, population genetics, medical genetics, human genetics, advanced medical genetics, cytogenetics, advanced cytogenetics, biochemical genetics, molecular cytogenetics advanced, cellular and molecular nutrition, cellular and molecular biology, advanced cancer genetics, principles of standardization, immunobiochemistry and analysis methods, in master's and specialized doctorate degrees and molecular cell biology courses, general genetics, hereditary diseases

Teaching Interests :

genetic engineering
genetic updates
molecular methods of disease diagnosis
medical genetics
advanced medical genetics
cytogenetics and advanced cytogenetics
biochemical genetics
cellular and molecular nutrition
advanced cancer genetics
hereditary diseases